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[Intracorneal granulomatous inflammation].

W Meyer-Riemann¹, C D Quentin, M Vogel

¹Universitäts-Augenklinik, Robert-Koch-Strasse 40, 37075 Göttingen.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|March 27, 2001

Summary

A rare corneal granuloma developed months after phototherapeutic keratectomy (PTK) in a patient with lattice corneal dystrophy. Histology revealed inflammatory cells, but a link to PTK was deemed unlikely.

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Area of Science:

Ophthalmology
Corneal Surgery
Pathology

Background:

Lattice corneal dystrophy is a hereditary condition affecting the cornea.
Phototherapeutic keratectomy (PTK) is a surgical procedure used to treat corneal irregularities.

Observation:

A 33-year-old man with lattice corneal dystrophy developed an intracorneal tumor 8 months after PTK.
No history of foreign body injury or clear cause for the tumor was identified.

Findings:

Histological examination of the excised tumor revealed a dense inflammatory infiltrate.
The infiltrate included epithelioid cells, histiocytes, lymphocytes, eosinophilic leukocytes, and Touton giant cells.
No signs of generalized granulomatous inflammation were present.

Implications:

This case presents a rare monosymptomatic intracorneal granulomatous infiltration.
The granuloma's occurrence months after PTK, without a clear link, is unusual.
Potential diagnoses include xanthogranuloma or sarcoidosis, though a pathogenetic connection to PTK is unlikely.

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