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Updated: Oct 9, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
[Study of the plasma adrenomedullin value in pregnancy induced hypertension patients]
Objective:
To investigate the relationship between adrenomedullin(ADM) and pregnancy induced hypertension(PIH).
Method:
The ADM values in the plasma from 12 normal term-pregnant women and 26 women with PIH were determined by specific radioimmunoassay.
Result:
(1) The ADM value in the PIH (24.67 +/- 1.27) ng/L increased significantly than that of normal pregnancy (19.16 +/- 1.17) ng/L (P < 0.05). (2) There were significant difference between severe(30.00 +/- 1.17) ng/L moderate (24.80 +/- 0.70) ng/L and mild (19.38 +/- 2.65) ng/L PIH groups (P < 0.001). (3) Significant positive correlation was found between plasma ADM value and mean arterial pressure (r = 0.775, P < 0.001).
Conclusion:
The ADM level is closely associated with PIH and may plan an important role in PIH.
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Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.