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[Recurrent epithelial ovarian cancer].

X Ding1, J Lang, K Shen

  • 1Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730.

Zhonghua Fu Chan Ke Za Zhi
|March 27, 2001
PubMed
Summary

Recurrent epithelial ovarian cancer is influenced by various factors including tumor stage and residual disease after surgery. Secondary cytoreductive surgery combined with chemotherapy improves survival rates for patients with recurrent ovarian cancer.

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Area of Science:

  • Gynecologic Oncology
  • Cancer Research
  • Clinical Medicine

Context:

  • Epithelial ovarian cancer recurrence presents a significant clinical challenge.
  • Understanding factors influencing recurrence is crucial for treatment strategies.
  • This study analyzes a retrospective cohort of ovarian cancer patients.

Purpose:

  • To identify key factors affecting the recurrence of epithelial ovarian cancer.
  • To evaluate treatment strategies for recurrent disease.
  • To improve patient survival outcomes.

Summary:

  • Histology, stage, tumor differentiation, chemotherapy, and residual disease post-cytoreductive surgery significantly impact ovarian cancer recurrence.
  • No residual disease correlated with longer recurrence time (17.2 months) versus residual disease (10.1 months).
  • Secondary cytoreductive surgery combined with chemotherapy demonstrated a higher five-year survival rate (27.3%) compared to chemotherapy alone (7.1%) or no therapy (4.8%).

Impact:

  • Findings guide the development of more effective treatment protocols for recurrent ovarian cancer.
  • Highlights the importance of optimal cytoreductive surgery and multimodal therapy.
  • Contributes to improving the prognosis for patients with recurrent epithelial ovarian cancer.

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