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Updated: Jul 28, 2026

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy
Published on: March 13, 2014
Characterisation of fatty acids in biological oil samples using comprehensive multidimensional gas chromatography
H J de Geus1, I Aidos, J de Boer
1Free University, Department of Analytical Chemistry and Applied Spectroscopy, Amsterdam, The Netherlands. gcxgc.work@gmx.net
Abstract:
Comprehensive multidimensional gas chromatography can adequately resolve very complex mixtures of analytes such as the fatty acid mixtures which are contained in, e.g., fish and vegetable oils. Well-ordered patterns are obtained in the two-dimensional separation plane which can be used to tentatively identify peaks when no standard is available. The technique which can also be used for quantification, i.e., quantitative ratio analysis, should be especially useful for fingerprinting purposes. Unravelling the composition of complex mixtures such as fish oils appears to be highly rewarding.
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