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Updated: Aug 8, 2026

In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions
Published on: June 11, 2015
The influence of thrombus components in mediating bacterial adhesion to biomaterials
N M Lamba1, J N Baumgartner, S L Cooper
1Department of Chemical Engineering, University of Delaware, Newark 19716, USA.
Abstract:
Thrombosis and infection represent the two largest limiting factors determining the long term success of implanted biomaterials. Infections associated with biomaterials are difficult to treat, and appear to evade the host defense systems. Mechanisms relating infection to thrombosis are described. Investigations into the role of receptors in mediating adhesion to thrombi are also discussed, in addition to strategies to reduce bacterial adhesion to biomaterial surfaces.
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