Related Experiment Video
Updated: Jul 28, 2026

Somatosensory Event-related Potentials from Orofacial Skin Stretch Stimulation
Published on: December 18, 2015
Coincidence detection or temporal integration? What the neurons in somatosensory cortex are doing
1Department of Neuroscience and Anatomy, Penn State University College of Medicine, Hershey, Pennsylvania 17033-2255, USA.
Abstract:
To assess the impact of thalamic synchronization on cortical responsiveness, we used conditional cross-correlation analysis to measure the probability of neuronal discharges in somatosensory cortex as a function of the time between discharges in pairs of simultaneously recorded neurons in the ventrobasal thalamus. Among 26 neuronal trios, we found that thalamocortical efficacy after synchronous thalamic activity was nearly twice as large as the efficacy rate obtained when pairs of thalamic neurons discharged asynchronously. Nearly half of these neuronal trios displayed cooperative effects in which the cortical discharge probability after synchronous thalamic events was larger than could be predicted from the efficacy rate of individual thalamic discharges. In these cases of heterosynaptic cooperativity, thalamocortical efficacy declined to asymptotic levels when the interspike intervals were >6-8 msec. These results indicate that thalamic synchronization has a significant impact on cortical responsiveness and suggest that neuronal synchronization may play a critical role in the transmission of sensory information from one brain region to another.
More Related Videos
07:52Simultaneous Recordings of Cortical Local Field Potentials and Electrocorticograms in Response to Nociceptive Laser Stimuli from Freely Moving Rats
Published on: January 7, 2019
06:18In Vivo Visualization of Spontaneous Activity in Neonatal Mouse Sensory Cortex at a Single-Neuron Resolution
Published on: November 21, 2023
Related Concept Videos
Somatosensation
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Sensory Perception: Organization of the Somatosensory System
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Overview of Somatic Sensory Pathways
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Somatosensory, Motor, and Association Cortex