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Correlation between serum testosterone levels and peripartal mood states
M Hohlagschwandtner1, P Husslein, C Klier
1Department of Obstetrics and Gynecology, University of Vienna, Vienna, Austria.
Acta Obstetricia Et Gynecologica Scandinavica
|March 27, 2001
Summary
Serum testosterone levels are linked to increased maternal depression and anger during the postpartum period. This study explored the connection between testosterone and mood changes in new mothers.
Area of Science:
- Reproductive Endocrinology
- Perinatal Psychiatry
- Women's Health
Background:
- Investigates the relationship between serum testosterone and mood in mothers.
- Conducted at the University Hospital of Vienna's Obstetrics and Gynecology department.
Purpose of the Study:
- To explore associations between serum testosterone levels and maternal peripartal mood states.
- Examine the correlation between testosterone and mood changes during pregnancy and the postpartum period.
Main Methods:
- Prospective study of 252 pregnant women at term (38-40 weeks' gestation).
- Collected blood samples for testosterone levels prepartum and on postpartum days 1 and 3.
- Assessed maternal mood using the McNair Profile of Mood States (POMS) from term pregnancy through hospital discharge.
Main Results:
- Serum testosterone levels showed significant correlations with maternal depression scores prepartum and on postpartum days 1 and 2.
- Testosterone concentrations also correlated with prepartum anger and anger on the third postpartum day.
- No significant correlations were found between testosterone and fatigue or vigor.
Conclusions:
- Serum testosterone levels are associated with maternal depression and anger in the early postpartum period.
- Findings suggest a hormonal influence on postpartum mood regulation.