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Updated: Oct 9, 2026

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
07:34

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System

Published on: May 5, 2018

Fetal diagnosis and management of congenital heart disease

M S Cohen1

  • 1Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, USA. cohenm@email.chop.edu

Clinics in Perinatology
|March 27, 2001
PubMed

Insights

Fetal echocardiography significantly improves congenital heart disease diagnosis and management. Serial studies reveal lesion progression, highlighting the importance of fetal diagnosis for pediatric cardiac care.

Area of Science:

  • Cardiology
  • Fetal Medicine
  • Pediatric Cardiology

Background:

  • Fetal echocardiography is crucial for diagnosing congenital heart disease (CHD).
  • Fetal circulation tolerates some heart lesions, but others severely impact fetal physiology.
  • Serial studies track lesion progression during gestation, offering insights into natural history.

Purpose of the Study:

  • To emphasize the impact of fetal echocardiography on CHD diagnosis and management.
  • To highlight the role of serial studies in understanding lesion progression.
  • To discuss the current status and future of fetal intervention.

Main Methods:

  • Review of existing literature on fetal echocardiography and congenital heart disease.
  • Analysis of natural history of various cardiac lesions during fetal development.
  • Evaluation of the role of fetal diagnosis in the overall management of pediatric cardiac conditions.

Main Results:

  • Fetal echocardiography has substantially advanced CHD diagnosis and management.
  • Understanding lesion progression during gestation is possible through serial studies.
  • While fetal cardiac surgery is not yet standard, fetal intervention for noncardiac disorders shows promise.

Conclusions:

  • Fetal diagnosis is an indispensable component of managing children with cardiac lesions.
  • Continued advancements in fetal imaging and intervention are expected.
  • Early and accurate fetal diagnosis optimizes outcomes for pediatric cardiac patients.

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