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Related Experiment Videos

Clinical experience with the MicroMed DeBakey ventricular assist device.

G P Noon1, D L Morley, S Irwin

  • 1Department of Surgery, Baylor College of Medicine, Houston, Texas, USA. gnoon@bcm.tmc.edu

The Annals of Thoracic Surgery
|March 27, 2001
PubMed
Summary

The MicroMed DeBakey ventricular assist device (VAD) offers crucial circulatory support for severe heart failure patients awaiting transplantation. Clinical trials show an 81% survival rate at 30 days post-implant.

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Area of Science:

  • Cardiovascular Medicine
  • Medical Devices
  • Surgical Technology

Background:

  • The MicroMed DeBakey ventricular assist device (VAD) is a pioneering long-term axial flow device.
  • It was the first of its kind to enter clinical trials as a bridge to cardiac transplantation.
  • Clinical trials commenced in Europe in 1998 and the US in 2000.

Purpose of the Study:

  • To evaluate the efficacy of the MicroMed DeBakey VAD in patients with end-stage heart failure.
  • To assess its role as a bridge to cardiac transplantation.
  • To understand the device's function and continuous flow in human subjects.

Main Methods:

  • Patients selected for the study were listed for cardiac transplantation and exhibited profound cardiac failure.
  • Exclusion criteria were limited to those typically preventing cardiac transplantation.

Related Experiment Videos

  • The study involved implanting the MicroMed DeBakey VAD.

    • Main Results:

    • As of September 2000, 51 patients received the MicroMed DeBakey VAD implant.
    • Detailed evaluation of the initial 32 patients was completed.
    • The 30-day survival probability following VAD implantation was 81%.

    Conclusions:

    • The MicroMed DeBakey VAD effectively provides circulatory support for patients with severe heart failure.
    • The device enables patients to recover and resume normal activities while awaiting transplantation.
    • Significant insights were gained regarding the device's performance and continuous flow in humans.