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The LionHeart LVD-2000: a completely implanted left ventricular assist device for chronic circulatory support
S M Mehta1, W E Pae, G Rosenberg
1Division of Cardiothoracic Surgery and Artificial Organs, The Milton S Hershey Medical Center, The Pennsylvania State University, Hershey 17033, USA. smehta@psu.edu
Insights
End-stage cardiac disease management is challenging. The LionHeart LVD-2000 left ventricular assist device offers a safe and effective chronic mechanical circulatory support solution, bridging patients for cardiac transplant.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- End-stage cardiac disease presents significant management challenges.
- Limited donor organs impact cardiac transplant viability.
- Mechanical circulatory support (MCS) is crucial for bridging patients to transplant.
Purpose of the Study:
- To provide an overview of the LionHeart LVD-2000, a fully implanted left ventricular assist system.
- To detail the implantation procedure and review preclinical findings.
- To present early clinical outcomes from European implants.
Main Methods:
- Development of a chronic MCS system over 30 years at Penn State University.
- Industrial partnership with Arrow International for the LionHeart LVD-2000.
- Synopsis of implantation procedures and review of preclinical and early clinical data.
Main Results:
- The LionHeart LVD-2000 system has demonstrated safety, efficacy, and reliability in early European implants.
- Transcutaneous energy transmission system validated.
- Compliance chamber functionality validated.
Conclusions:
- The LionHeart LVD-2000 represents a significant advancement in chronic mechanical circulatory support.
- The system offers a viable option for patients with end-stage cardiac disease awaiting transplant.
- Validated components ensure reliable long-term device performance.
Abstract:
Management of patients with end-stage cardiac disease remains a vexing problem. Limitations in medical management and a fixed supply of donor organs for cardiac transplant have a continued impact on this growing population of patients. Mechanical circulatory support has proved very successful as a means of bridging patients to cardiac transplant when all medical options have been exhausted. The development of a chronic system of circulatory support has been underway at the Pennsylvania State University for nearly 30 years. These efforts have been recently merged with the industrial partnership with Arrow International toward the development of the LionHeart LVD-2000 (Arrow International, Reading, PA) completely implanted left ventricular support system. We present an overview of the system, details of implantation, a review of preclinical studies, and a synopsis of the first European implants. Early results have demonstrated the system to be safe, effective, and reliable. Transcutaneous energy transmission and the compliance chamber have been validated.
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