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Related Experiment Videos

The HeartSaver left ventricular assist device: an update.

P J Hendry1, T V Mussivand, R G Masters

  • 1Division of Cardiac Surgery, University of Ottawa Heart Institute, Ontario, Canada.

The Annals of Thoracic Surgery
|March 27, 2001
PubMed
Summary

The HeartSaver Ventricular Assist Device (VAD) is a fully implantable system designed to overcome limitations of current VADs. Preclinical testing shows promising results for this portable, transcutaneous-powered device.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Technology
  • Medical Devices

Background:

  • Ventricular assist devices (VADs) are crucial for end-stage heart failure patients awaiting transplantation or recovery.
  • Existing VADs face limitations due to percutaneous connections.
  • The HeartSaver VAD aims for a completely implantable, portable system with transcutaneous power and telemetry.

Purpose of the Study:

  • To evaluate the preclinical performance of the HeartSaver VAD, a novel, fully implantable ventricular assist device.
  • To assess modifications and optimizations made to the device's components and system integration.

Main Methods:

  • The Series II preclinical version of the HeartSaver VAD underwent in vitro (mock loop) and in vivo (bovine model) testing.
  • Accumulated operational data from mock loop trials and acute experiments in a bovine model were analyzed.

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Main Results:

  • Seventeen Series II devices operated for a cumulative 900 days on mock loops.
  • Mean pump output reached 10.4 +/- 1.1 L/min.
  • Key modifications included cannula redesign, lithium-ion battery integration, optimized transcutaneous energy/telemetry, and improved controller reliability.

Conclusions:

  • Significant modifications were implemented to enhance the HeartSaver VAD's performance.
  • The final design is nearing completion for formal preclinical testing prior to clinical trials.