Treatment of infrapopliteal occlusive disease by high-speed rotational atherectomy: initial and mid-term results
T Jahnke1, J Link, S Müller-Hülsbeck
1Klinik für Diagnostiche Radiologie, Christian-Albrechts-Universität zu Kiel, Uniklinik Regensburg, Germany.
Insights
High-speed rotational atherectomy (HSRA) showed high initial success for infrapopliteal arterial disease but poor mid-term patency. HSRA is not recommended as a primary treatment for these lesions.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Artery Disease
Background:
- Infrapopliteal arterial occlusive disease significantly impacts patient mobility and quality of life.
- Effective treatment strategies for infrapopliteal lesions are crucial for limb salvage and symptom relief.
Purpose of the Study:
- To evaluate the effectiveness and patency rates of high-speed rotational atherectomy (HSRA) in treating infrapopliteal arterial occlusive disease.
- To determine the mid-term outcomes of HSRA in this patient population.
Main Methods:
- A total of 19 infrapopliteal lesions in 15 patients were treated with HSRA using the Rotablator device.
- Patients underwent clinical assessment, treadmill exercise, and Doppler sonography at 1, 3, and 6 months post-intervention.
- Control angiography was performed at 6 months to assess lesion patency.
Main Results:
- HSRA achieved an initial technical success rate of 94% (14 of 15 patients).
- Ankle-brachial index (ABI) improved significantly post-intervention but showed a declining trend at 6 months.
- Only one of 12 assessed lesions remained patent without significant restenosis at 6 months, leading to study termination.
Conclusions:
- HSRA demonstrates a high initial technical success rate for infrapopliteal occlusive disease.
- However, the mid-term patency rates are unacceptably poor.
- HSRA is not recommended for the primary treatment of infrapopliteal arterial occlusive disease.
Purpose:
To assess the effectiveness and patency rates of high-speed rotational atherectomy (HSRA) for the treatment of infrapopliteal arterial occlusive disease.
Material And Methods:
During an 18-month period, a total of 19 infrapopliteal lesions in 15 consecutive patients were treated primarily by HSRA with use of the Rotablator device. Patients were followed up with documentation of clinical symptoms, standardized treadmill exercise, and Doppler sonography at 1, 3, and 6 months. Control angiography was performed 6 months after primary treatment.
Results:
HSRA was initially successful in 14 of 15 patients, yielding an initial technical success rate of 94%. Percutaneous treatment induced an improvement of the ankle-brachial index (ABI) from 0.6 +/- 0.09 to 0.86 +/- 0.2 after intervention (P < .0001). Doppler analysis showed a mean ABI of 0.85 +/- 0.2 (P < .001) at 1 month, 0.72 +/- 0.2 (P = .012) at 3 months, and 0.7 +/- 0.2 (P = .08) at 6 months after initial therapy. Although six patients were lost to follow-up at various times, control angiography at 6 months was carried out in nine of 15 patients, allowing direct assessment of 12 of 19 treated lesions. Among six high-grade restenoses and five total occlusions in the treated vascular segments, only one arterial lumen (of 12) remained patent without presenting a hemodynamically relevant restenosis. These results led to termination of the study.
Conclusion:
Although HSRA for the treatment of infrapopliteal occlusive disease yields a very high initial technical success rate, mid-term results are extremely poor. Therefore, HSRA cannot be recommended for primary treatment of this type of lesion.
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