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The synthesis of beta-peptides containing guanidino groups
1The Salk Institute for Biological Studies, San Diego, CA 92186, USA.
Bioorganic & Medicinal Chemistry Letters
|March 27, 2001
Abstract:
The synthesis of the beta-peptide 1 by the postsynthetic modification of the corresponding amino-containing peptide 3 is described. The potential of 1 to act as a template for the ligation of complementary negatively-charged peptides is discussed.