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RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency
A J Collis1, M L Foster, F Halley
1Aventis Pharma, Dagenham Research Centre, Essex, UK.
Bioorganic & Medicinal Chemistry Letters
|March 27, 2001
Abstract:
Following the discovery of RPR200765, a series of pyrimidine analogues have been prepared as backups. Amongst them, RPR203494 was identified with a better in vitro profile than RPR200765A.
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