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Erythema multiforme infantum atrophicans.

R D Azulay, L P Quevedo, R D Gifueria

    International Journal of Dermatology
    |January 1, 1975
    PubMed
    Summary
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    A rare case of erythema multiforme presented with a distinctive rash and facial aging. Histopathology revealed elastic fiber loss in the atrophic stage, offering new insights into this condition.

    Area of Science:

    • Dermatology
    • Pathology

    Background:

    • Erythema multiforme is an acute, immune-mediated mucocutaneous condition.
    • It typically presents with characteristic target lesions.

    Purpose of the Study:

    • To describe a novel case of erythema multiforme.
    • To detail the clinical and histopathological features, including late-stage changes.

    Main Methods:

    • Clinical observation of a patient with erythema multiforme.
    • Histopathological examination of skin lesions during acute and atrophic phases.

    Main Results:

    • The case exhibited a multiforme eruption of erythematous papules, plaques, and bullae.
    • The acute phase evolved into an atrophic stage with noticeable facial aging.

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  • Histopathology confirmed erythema multiforme in the acute phase and demonstrated a disappearance of elastic fibers in the atrophic stage.
  • Conclusions:

    • This case highlights the potential for significant skin atrophy and aging-like changes in erythema multiforme.
    • The observed loss of elastic fibers provides a histopathological correlate for the atrophic changes.