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Identification and characterization of a gene encoding a 35-kDa protein from Mycobacterium avium subspecies
K D Banasure1, S H Basagoudanavar, P Chaudhury
1National Biotechnology Centre, Indian Research Institute, Izannagar, India.
FEMS Microbiology Letters
|March 27, 2001
Abstract:
Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, a chronic enteritis in ruminants. A gene homologous to that of 35-kDa antigen of Mycobacterium leprae was cloned and sequenced from Mycobacterium paratuberculosis. The database searches revealed 82.79% and 95.67% similarities of its nucleotide sequence, with those of immunodominant 35-kDa protein of M. leprae and M. avium, respectively.