Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Oogenesis: Setting one sister above the rest.

C Navarro¹, R Lehmann, J Morris

¹Developmental Genetics Program, Skirball Institute, Howard Hughes Medical Institute, Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA.

Current Biology : CB

|March 27, 2001

Summary

The Par-1 protein plays crucial roles early in oogenesis, influencing both microtubule-dependent and independent processes. This expands our understanding beyond its known function in fruit fly oocyte development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Management of menopausal hot flushes. Recommendations from the Spanish Menopause Society.

European journal of obstetrics & gynecology and reproductive biology: X·2025

Same author

Prospective monitoring of adverse events following vaccination with Modified vaccinia Ankara - Bavarian Nordic (MVA-BN) administered to a Canadian population at risk of Mpox: A Canadian Immunization Research Network study.

Vaccine·2024

Same author

The role of defects in the persistent photoconductivity of BaSnO<sub>3</sub>thin films.

Journal of physics. Condensed matter : an Institute of Physics journal·2023

Same author

Diagnostic accuracy of combining C-Reactive protein and Alvarado Score among 2-to-20-year-old patients with acute appendicitis suspected presenting to Emergency Departments.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2021

Same author

Antibodies elicited by the CaniLeish® vaccine: long-term clinical follow-up study of dogs in Spain.

Parasitology research·2021

Same author

The use of autologous platelet-rich plasma (PRP) versus no intervention in women with low ovarian reserve undergoing fertility treatment: a non-randomized interventional study.

Journal of assisted reproduction and genetics·2020

Area of Science:

Developmental Biology
Cell Biology
Genetics

Background:

The Partition-defective 1 (Par-1) protein is known for its role in establishing the anterior-posterior axis in Drosophila oocytes.
Early oogenesis involves complex cellular events that are critical for proper development.

Purpose of the Study:

To investigate the functions of the Par-1 protein beyond its established role in anterior-posterior patterning.
To explore the early roles of Par-1 during oogenesis, including its potential involvement in microtubule-dependent and independent pathways.

Main Methods:

Utilized genetic analysis in Drosophila melanogaster.
Investigated the function of Par-1 protein during early stages of oogenesis.

Main Results:

Related Experiment Videos

The Par-1 protein exhibits functions early in oogenesis that are distinct from its role in anterior-posterior patterning.
These early roles involve both microtubule-dependent and microtubule-independent cellular mechanisms.

Conclusions:

The Par-1 protein has multifaceted roles in early oogenesis, highlighting its broader importance in developmental processes.
Further research into these distinct functions can elucidate novel mechanisms in cell polarity and development.