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Cytokines: IL-21 joins the gamma(c)-dependent network?
C A Vosshenrich1, J P Di Santo
1Unité des Cytokines et Développement Lymphoïde, Institut Pasteur, 25 rue du Dr Roux, 75742, Paris, France. vosshenr@pasteur.fr
Current Biology : CB
|March 27, 2001
Abstract:
The discovery of the cytokine IL-21 adds another member to the ever-growing list of small secreted molecules that have potent effects on lymphoid cells. Initial characterization of the IL-21 receptor complex suggests that IL-21 may belong to the cytokine family whose receptors share the common gamma chain, gamma(c).