True carcinosarcoma of the esophagus with osteosarcoma
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Updated: Oct 9, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
Y Nakakubo1, S Okushiba, K Ohno
1Second Department of Surgery, Hokkaido University School of Medicine, N-14, W-5, Sapporo 060-8648, Japan.
Abstract:
We experienced a case of true carcinosarcoma of the esophagus with osteosarcoma. Computed tomography scan revealed calcification of the tumor. Immunohistochemically, vimentin staining was positive, and osteoid formation was found in the sarcomatous portion. It was clear that the lesion contained osteosarcoma of mesenchymal origin, and thus we diagnosed it as true carcinosarcoma.
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