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A self-contained calibration unit for use with intracellular recording systems
Journal of Applied Physiology
|May 1, 1975
Summary
A new, affordable solid-state device calibrates amplifiers and recorders for microelectrode studies. This battery-powered instrument provides essential signals for amplitude, capacitance neutralization, and differentiating circuits, simplifying calibration during recording.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Instrumentation
Background:
- Microelectrode studies require precise calibration of recording equipment.
- Existing calibration methods can be complex or expensive.
Purpose of the Study:
- To describe a novel, inexpensive solid-state device for calibrating amplifiers and recorders in microelectrode research.
- To provide three distinct calibration signals for comprehensive instrument assessment.
Main Methods:
- The device is inserted between the ground electrode and the amplifier.
- It generates a 100 mV DC signal for amplitude calibration.
- It produces a variable-frequency square wave for capacitance neutralization and a variable-rate square wave for differentiating circuit calibration.
Main Results:
- The device offers a cost-effective solution for essential calibration tasks.
- It provides three crucial signals: DC amplitude, square wave for capacitance, and variable-rise/fall square wave for differentiation.
- The instrument is self-contained, battery-powered, and designed for in-circuit use.
Conclusions:
- This device simplifies and enhances the calibration process for microelectrode recordings.
- Its affordability and versatility make it a valuable tool for researchers.
- Calibration can be performed with or without the microelectrode in place, offering flexibility.
