Image quality and dose in film-screen magnification mammography

Extended exposure times in magnification mammography are a result of the reduced X-ray tube currents required for a small focal spot. The consequences of this are the potential for reduced image quality through motion blur during exposure as well as the onset of film reciprocity law failure. Previous investigators have suggested increasing the X-ray tube potential as a practical mechanism for reducing exposure times in magnification mammography and have demonstrated negligible image quality degradation at least up to 32 kVp. This paper describes a film-screen magnification mammography study that expands upon this previous work to investigate the magnitude of the reduction of breast mean glandular dose and exposure time and the changes in subjective image quality (visibility of low contrast details in an RMI 152 phantom) with increases in tube potential between 28 kVp and 35 kVp. Measures of changes in the radiographic contrast and in the scatter-to-primary ratio (SPR) in magnification geometry as a function of tube potential were also obtained. Evidence for reciprocity law failure was also assessed. For a constant film optical density, increasing the X-ray tube potential from 28 kVp to 35 kVp reduced the mean glandular dose from 3.9 mGy to 2.7 mGy and reduced the exposure time from 3.2 s to 1.0 s. Over this range, the detection rate of fibrils and microcalcification-mimicking specks did not vary with tube potential at the 0.05 level of significance. It was found that only the low contrast mass detail detection rate at 35 kVp was significantly less than that at 28 kVp. The measured radiographic contrast decreased with tube potential and the SPR increased with tube potential. However, both changes were weak, and linear regressions determined that the 95% confidence intervals of the slopes relating both contrast and SPR with tube potential encompassed zero. It is concluded that magnification mammography performed at 34 kVp yields significant reductions in exposure time and mean glandular dose, with a detail detection capability similar to that at 28 kVp.