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5-fluorouracil extravasation following port failure
Summary
A standard Huber needle perforated a patient's implantable venous port, causing cytotoxic extravasation of 5-fluorouracil. This case highlights a rare complication of central venous port use.
Area of Science:
- Oncology
- Vascular Surgery
- Radiology
Background:
- Implantable venous ports are common devices for long-term chemotherapy administration.
- Proper needle insertion technique is crucial to prevent device-related complications.
Observation:
- A patient receiving 5-fluorouracil experienced hemoserous discharge and signs of inflammation at the needle entry site.
- Physical examination revealed warmth, erythema, and swelling of the left chest wall.
- A venogram confirmed significant extravasation localized around the left port reservoir.
Findings:
- The implantable venous port was perforated by a standard Huber needle.
- Inspection post-removal revealed the needle had penetrated the port's base plate.
- Cytotoxic extravasation occurred due to the needle-induced port perforation.
Implications:
- This case suggests needle perforation of implantable ports is a potential complication.
- Enhanced vigilance during port access and needle selection may be warranted.
- Consideration should be given to adding this complication to the known sequelae of central venous port use.