Related Experiment Video
Updated: Aug 6, 2026
08:21
A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
Tuberculous abdominal lymphadenopathy causing reversible renovascular hypertension
S Puri1, S B Khurana, S Malhotra
1Department of Medicine, Dayanand Medical College and Hospital, Ludhiana-141 001.
The Journal of the Association of Physicians of India
|March 29, 2001
Summary
A rare cause of renovascular hypertension was identified in a young male: abdominal lymphadenopathy due to tuberculosis. Treatment with antitubercular medication successfully controlled both the infection and the high blood pressure.
Area of Science:
- Nephrology
- Infectious Diseases
- Cardiology
Background:
- Renovascular hypertension, a less common cause of elevated blood pressure, can arise from extrinsic compression of renal arteries.
- Retroperitoneal structures, including lymph nodes, can rarely cause such compression, leading to hypertension.
- Metastatic lymphadenopathy is a known, though infrequent, cause of renovascular hypertension.
Observation:
- A 21-year-old male presented with hypertension.
- The hypertension was found to be caused by abdominal lymphadenopathy.
- The lymphadenopathy was diagnosed as tuberculosis.
Findings:
- The patient's hypertension resolved with antitubercular therapy.
- This case highlights an unusual etiology for renovascular hypertension.
- Abdominal tubercular lymphadenopathy was identified as a rare complication leading to hypertension.
Implications:
- Antitubercular treatment can effectively manage hypertension secondary to tubercular lymphadenopathy.
- Clinicians should consider tuberculosis as a potential cause of renovascular hypertension in endemic areas.
- This case broadens the understanding of rare complications associated with tuberculosis.
Related Concept Videos
01:18Hypertension and Regulation of Blood Pressure
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
01:23Rheumatic Heart Disease I: Introduction
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
01:29Hypertension II: Pathophysiology
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
01:24Nephrotic Syndrome I : Introduction
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
01:29Acute Kidney Injury II: Pathophysiology
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
01:28Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...