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Colonic tuberculosis: colonoscopic appearance and clinico-pathologic analysis.

H S Das1, P Rathi, P Sawant

  • 1Department of Gastroenterology and Pathology, LT Municipal Medical College and LT Municipal General Hospital, Sion, Mumbai 400 022.

The Journal of the Association of Physicians of India
|March 29, 2001
PubMed
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Colonoscopy is crucial for diagnosing intestinal tuberculosis, especially with the rise of acquired immunodeficiency syndrome (AIDS). Characteristic colonoscopic findings, alongside histopathology, aid in identifying this infection.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pulmonology

Background:

  • The acquired immunodeficiency syndrome (AIDS) epidemic has led to a resurgence of interest in intestinal tuberculosis.
  • Colonoscopy and colonoscopy-directed histology are increasingly emphasized for diagnosing intestinal tuberculosis.

Purpose of the Study:

  • To identify the colonoscopic features of intestinal tuberculosis.
  • To correlate colonoscopic findings with clinicopathological data in patients with intestinal tuberculosis.

Main Methods:

  • A study of twenty-one patients with intestinal tuberculosis between 1993 and 1997.
  • All patients underwent colonoscopy, with biopsy specimens collected from lesions.

Main Results:

Related Experiment Videos

  • Ileocecal disease was observed in 9 patients, with contiguous involvement in 8, and segmental colonic tuberculosis in 4.
  • Colonoscopic findings included nodules (7), nodules with ulcerations (3), ulcerations alone (7), nodules with strictures (3), and a polypoidal mass (1).
  • Histopathology revealed granulomas in 8 cases.

    • Conclusions:

    • While bacteriological and histological assessments are essential, colonoscopic appearances are vital for diagnosing intestinal tuberculosis.
    • Antituberculous chemotherapy is recommended for patients with high clinical suspicion based on colonoscopic findings, after excluding other causes via histopathology.