Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sonoclot analysis in healthy children.

E G Pivalizza1, P J Pivalizza, S Kee

  • 1Department of Anesthesiology, University of Texas Health Science Center, Houston 77030, USA. Evan.G.Pivalizza@uth.tmc.edu

Anesthesia and Analgesia
|March 29, 2001
PubMed
Summary

This study establishes normal Sonoclot device ranges for healthy pediatric surgical patients. These findings provide crucial data for accurate coagulation management in children, avoiding adult data extrapolation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of a hybrid technique of simultaneous videolaryngoscopy with flexible bronchoscopy in children with difficult direct laryngoscopy in the Pediatric Difficult Intubation Registry.

Anaesthesia·2023
Same author

A System-Wide Population Health Value Approach to Reduce Hospitalization Among Chronic Kidney Disease Patients: an Observational Study.

Journal of general internal medicine·2020
Same author

Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study-A Prospective Randomized Trial).

Anesthesia and analgesia·2017
Same author

Use of deep laryngeal oxygen insufflation during laryngoscopy in children: a randomized clinical trial.

British journal of anaesthesia·2016
Same author

Peripheral nerve catheters in children: an analysis of safety and practice patterns from the pediatric regional anesthesia network (PRAN).

British journal of anaesthesia·2015
Same author

Hidden implications: potential antiplatelet effects of adjuvant anaesthetic agents.

Anaesthesia and intensive care·2013

Area of Science:

  • Pediatric Coagulation
  • Hemostasis Monitoring
  • Medical Device Validation

Background:

  • Limited data exists for Sonoclot device use in normal pediatric patients.
  • The Sonoclot device is utilized in critical pediatric surgeries involving coagulation abnormalities.
  • Establishing pediatric-specific normal ranges is essential for accurate clinical interpretation.

Purpose of the Study:

  • To determine normal data ranges for Sonoclot variables in healthy pediatric surgical patients.
  • To compare Sonoclot measurements across different pediatric age groups and adults.
  • To provide a basis for improved coagulation management in pediatric care.

Main Methods:

  • Blood samples were collected from 95 healthy pediatric surgical patients post-anesthetic induction.

Related Experiment Videos

  • Sonoclot activated clotting time, clot formation rate, time to peak amplitude, and peak amplitude were measured.
  • Data were analyzed and compared across four pediatric age groups (<12 mo, 13-24 mo, 25-48 mo, 49 mo-9 yr) and an adult group.

    • Main Results:

    • Sonoclot activated clotting time differed significantly between the <12-month group and the oldest pediatric group, and between adults and the oldest pediatric group.
    • All measured Sonoclot activated clotting times fell within anticipated normal ranges.
    • No significant differences were observed in clot formation rate, time to peak amplitude, or peak amplitude across the age groups.

    Conclusions:

    • This study presents the first published Sonoclot variables for healthy pediatric surgical patients.
    • The established pediatric normal ranges facilitate accurate clinical coagulation management.
    • These findings help avoid the application of extrapolated adult data to pediatric patients, improving care.