Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genes and attention deficit hyperactivity disorder.

J Swanson1, M Posner, J Fusella

  • 1Child Development Center, University of California at Irvine, 19722 MacArthur Boulevard, Irvine, CA 92612, USA. jmswanso@uci,edu

Current Psychiatry Reports
|March 29, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

miR-216a rescues dexamethasone suppression of osteogenesis, promotes osteoblast differentiation and enhances bone formation, by regulating c-Cbl-mediated PI3K/AKT pathway.

Cell death and differentiation·2015
Same author

Distributions of topological observables in inclusive three- and four-jet events in pp collisions at [Formula: see text][Formula: see text].

The European physical journal. C, Particles and fields·2015
Same author

Evidence for Collective Multiparticle Correlations in p-Pb Collisions.

Physical review letters·2015
Same author

Constraints on parton distribution functions and extraction of the strong coupling constant from the inclusive jet cross section in pp collisions at [Formula: see text][Formula: see text].

The European physical journal. C, Particles and fields·2015
Same author

Search for a standard model Higgs boson produced in association with a top-quark pair and decaying to bottom quarks using a matrix element method.

The European physical journal. C, Particles and fields·2015
Same author

Search for dark matter, extra dimensions, and unparticles in monojet events in proton-proton collisions at [Formula: see text][Formula: see text].

The European physical journal. C, Particles and fields·2015
Same journal

Child and Adolescent Psychiatry in the Far East: Findings from Multi-National Surveys.

Current psychiatry reports·2026
Same journal

Involuntary Celibacy in the Digital Age: a Critical Narrative Review of the Incel Phenomenon, Mental Health Burden, Ideological Pathways, and Public Health Implications.

Current psychiatry reports·2026
Same journal

Is Technology Remaking Therapy: The Screen and the Self: Telepsychiatry, AI Therapy, and the Defense Against Intimacy.

Current psychiatry reports·2026
Same journal

Bridging Gaps in Perinatal Mental Health: A Review of Peer and Non-specialist Supports for Racially, Ethnically and Culturally Diverse Communities in the U.S.

Current psychiatry reports·2026
Same journal

Psychosocial Preparedness for Disasters: A Scoping Review of International Models and Public Health Priorities.

Current psychiatry reports·2026
Same journal

Artificial Intelligence in Child and Adolescent Psychiatry: A Narrative Review of Recent Clinical Applications and Ethical Considerations.

Current psychiatry reports·2026
See all related articles

Molecular genetic studies of attention deficit hyperactivity disorder (ADHD) examined dopamine pathway genes like DAT and DRD4. Research is ongoing to identify more genes contributing to this complex neurodevelopmental disorder.

Area of Science:

  • Neurogenetics
  • Psychiatric Genetics

Background:

  • Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder.
  • Dopamine pathway genes, including DAT and DRD4, are implicated in ADHD etiology and stimulant treatment response.
  • Initial genetic association studies have yielded mixed results, suggesting small effect sizes.

Purpose of the Study:

  • To review the initial molecular genetic findings for ADHD, focusing on DAT and DRD4.
  • To discuss the replication status of early candidate gene findings.
  • To highlight emerging research on additional genes contributing to ADHD's genetic basis.

Main Methods:

  • Literature review of published molecular genetic studies on ADHD.
  • Analysis of findings related to DAT and DRD4 gene associations.

Related Experiment Videos

  • Synthesis of emerging research on novel candidate genes.

    • Main Results:

    • Early studies identified weak associations between DAT and DRD4 genes and ADHD.
    • Replication of these initial findings has been inconsistent across studies.
    • Ongoing research is exploring a broader range of genes for ADHD susceptibility.

    Conclusions:

    • The genetic architecture of ADHD is complex, involving multiple genes with small effects.
    • Further research is needed to fully elucidate the genetic underpinnings of ADHD.
    • Identifying additional ADHD-associated genes is crucial for understanding its etiology and developing targeted treatments.