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Updated: Aug 5, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
The treatment of intrabony defects with bone grafts
P S Rosen1, M A Reynolds, G M Bowers
1Department of Periodontics, Baltimore College of Dental Surgery, University of Maryland Dental School, Baltimore, Maryland, USA.
Abstract:
There is substantial clinical and histological evidence that support the concept that extraoral and intraoral autogenous bone grafts and demineralized freeze-dried bone allografts are effective regenerative materials in the treatment of intrabony defects. Moreover, long-term evaluations currently available suggest that the regenerative gains achieved remain clinically stable. Synthetic grafts may result in improved probing depths and clinical attachment levels but have yet to demonstrate the ability to initiate or enhance the formation of a new attachment apparatus.
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