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Four patients with AL amyloidosis treated with high-dose chemotherapy and autologous stem cell transplantation
1Charité University Hospital, Department of Haematology, Oncology and Tumour Immunology, Humboldt University of Berlin, Germany.
Bone Marrow Transplantation
|March 30, 2001
Abstract:
Four patients with AL amyloidosis underwent high-dose chemotherapy and autologous stem cell transplantation at our institutions. Here, we report the clinical courses and outcomes in these patients. Two patients with multi-organ amyloid deposits including cardiac involvement died within 12 days after high-dose chemotherapy. However, in the other two patients, one of whom was suffering from amyloid-related cardiac failure, a significant improvement of organ function was achieved.
