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Related Experiment Videos

Complications associated with intraperitoneal chemotherapy catheters.

S Makhija1, M Leitao, P Sabbatini

  • 1Department of Gynecologic Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Gynecologic Oncology
|March 30, 2001
PubMed
Summary

Subcutaneous intraperitoneal (ip) catheters for ovarian cancer chemotherapy show a 10% complication rate, with infection and obstruction being most common. Avoiding bowel surgery and using laparoscopy for placement may reduce these risks.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Medical Devices

Background:

  • Intraperitoneal (ip) chemotherapy is a treatment for advanced ovarian cancer.
  • Subcutaneous ip catheters facilitate ip chemotherapy delivery.
  • Complication rates associated with these catheters require evaluation.

Purpose of the Study:

  • To determine the complication rate of subcutaneous ip catheters in advanced ovarian cancer patients.
  • To identify predisposing risk factors for these complications.

Main Methods:

  • Retrospective chart review of 301 patients receiving ip chemotherapy via subcutaneous Bardport catheters.
  • Data collected from December 1989 to May 1997 at Memorial Sloan--Kettering Cancer Center.
  • Analysis of complication types, placement methods, and chemotherapy regimens.

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Main Results:

  • A 10% complication rate (30/301 patients) was observed, including inflow obstruction (6.3%) and infection (3.6%).
  • Catheter malfunction or infection led to chemotherapy cessation in 7% of patients.
  • Catheter placement during laparotomy was associated with higher complication rates compared to laparoscopy or separate procedures.

Conclusions:

  • Subcutaneous ip catheters have a lower complication rate than previously reported.
  • Avoiding ip catheter insertion during bowel surgery and opting for laparoscopic placement may decrease complications.
  • These findings support optimizing surgical techniques for ip catheter placement.