Related Experiment Video
Updated: Aug 11, 2026
![Solid-phase Synthesis of [4.4] Spirocyclic Oximes](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58508.jpg&w=3840&q=50)
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
Rigid, cross-conjugated macrocycles: a cyclic alternative to 4,4'-bipyridines in supramolecular chemistry
K Campbell1, R McDonald, N R Branda
1Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2 Canada.
Abstract:
[structure: see text]. The synthesis of two fully conjugated, rigid macrocyclic analogues to 4,4'-bipyridine is described. The use of these macrocycles in self-assembly processes is demonstrated by axial coordination to metalloporphyrins, and one system (R = Me) has been characterized by single-crystal X-ray crystallography.
More Related Videos
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
14:11Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Related Concept Videos
Thermal and Photochemical Electrocyclic Reactions: Overview
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Woodward–Hoffmann Selection Rules and Microscopic Reversibility
Cycloaddition Reactions: Overview
Pericyclic Reactions: Introduction
Pericyclic reactions can be classified into three categories: electrocyclic reactions, cycloaddition reactions, and sigmatropic rearrangements. Electrocyclic reactions and sigmatropic rearrangements are...
Cycloaddition Reactions: MO Requirements for Thermal Activation