Renal functional abnormalities in post-unilateral ureteral obstruction in man: a comparison of these defects to...

The failure of fluid and electrolyte conservation in post-obstructive diuresis has not been demonstrated after release of unilateral ureteral obstruction. Despite this, balance and renal function studies in patients with this disorder indicate similar renal defects. The clinical difference is caused by a markedly low glomerular filtration rate in unilateral problems that prevents the excessive losses found with total obstruction.