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Destructive eyelid lesions in sarcoidosis
M Moin1, R C Kersten, F Bernardini
1Department of Ophthalmology, University of Cincinnati, Ohio, USA.
Ophthalmic Plastic and Reconstructive Surgery
|April 3, 2001
Summary
Sarcoidosis can rarely cause severe lower eyelid destruction. Controlling this systemic inflammatory disease is crucial before any eyelid reconstruction surgery.
Area of Science:
- Ophthalmology
- Dermatology
- Pathology
Background:
- Sarcoidosis is a multisystem inflammatory disease characterized by non-caseating granulomas.
- Ocular involvement is common in sarcoidosis, but eyelid destruction is rare.
Observation:
- A 43-year-old man with known systemic sarcoidosis presented with bilateral destructive lower eyelid lesions.
- The patient developed cicatricial entropion due to the eyelid damage.
Findings:
- Histopathology confirmed sarcoid granulomas in the eyelid lesions.
- Systemic treatment with prednisone and methotrexate halted disease progression.
Implications:
- Sarcoidosis can lead to full-thickness eyelid destruction, a rare but serious complication.
- Controlling active sarcoidosis inflammation is essential prior to surgical eyelid reconstruction.