Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glabellar rhytids in thyroid-associated orbitopathy.

N D Saks1, M A Burnstine, A M Putterman

  • 1Department of Ophthalmology, Advocate Medical Group, Park Ridge, Illinois, USA.

Ophthalmic Plastic and Reconstructive Surgery
|April 3, 2001
PubMed
Summary

Glabellar rhytids are common in thyroid-associated orbitopathy (TAO). More severe wrinkles correlate with double vision (diplopia) and multiple disease signs in TAO patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Technique for modified transantral orbital decompression for improved cosmesis in stable thyroid eye disease.

International journal of oral and maxillofacial surgery·2021
Same author

Management of the lower eyelid.

Aesthetic surgery journal·2009
Same author

MR imaging of orbital inflammatory syndrome, orbital cellulitis, and orbital lymphoid lesions: the role of diffusion-weighted imaging.

AJNR. American journal of neuroradiology·2008
Same author

Migration of intraocular silicone oil into the subconjunctival space and orbit through an Ahmed glaucoma valve.

American journal of ophthalmology·2001
Same author

Internal levator advancement by Müller's muscle-conjunctival resection: technique and review.

Archives of facial plastic surgery·2001
Same author

Lacrimal canalicular diverticulum: a cause of epiphora and discharge.

Ophthalmic plastic and reconstructive surgery·2000

Area of Science:

  • Ophthalmology
  • Endocrinology

Background:

  • Thyroid-associated orbitopathy (TAO) is an autoimmune condition affecting the eye and surrounding tissues.
  • Glabellar rhytids, or forehead wrinkles, are common cosmetic concerns.

Purpose of the Study:

  • To investigate the correlation between the presence and severity of glabellar rhytids and the overall disease severity in patients diagnosed with TAO.

Main Methods:

  • A retrospective review of 113 new patient visits for TAO.
  • Ocular features like visual acuity, optic nerve status, proptosis, strabismus, and eyelid position were assessed.
  • Glabellar rhytid severity was graded using clinical photographs and correlated with clinical findings using the Fisher exact test.

Main Results:

Related Experiment Videos

  • Glabellar rhytids were observed in 82.5% of the 97 included patients.
  • Eyelid retraction was nearly universal (98%).
  • More severe rhytids were associated with diplopia (p < 0.05) and a higher number of abnormal clinical findings.

    • Conclusions:

    • Glabellar rhytids are a frequent clinical sign in patients with TAO.
    • The presence of glabellar rhytids, particularly more severe ones, may indicate a greater disease burden, including diplopia and multiple disease manifestations.