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Related Experiment Videos

Attention Deficit Hyperactivity Disorder.

Bennett A. Shaywitz1, Jack M. Fletcher, Sally E. Shaywitz

  • 1Department of Pediatrics, Yale University School of Medicine, P.O. Box 3333, New Haven, CT 06520-8064, USA. Bennett.Shaywitz@yale.edu

Current Treatment Options in Neurology
|April 3, 2001
PubMed
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Stimulant medications are the most effective treatment for attention deficit hyperactivity disorder (ADHD). New research indicates methylphenidate (MPH) and behavioral therapy are superior to other approaches for ADHD management.

Area of Science:

  • Child and Adolescent Psychiatry
  • Neurodevelopmental Disorders
  • Pharmacology

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) management involves pharmacologic and nonpharmacologic strategies.
  • Recent advancements include an evidence-based report and the Multisite Multimodal Treatment Study (MTA).

Purpose of the Study:

  • To review current evidence on ADHD treatment efficacy.
  • To compare pharmacologic and nonpharmacologic interventions for ADHD.

Main Methods:

  • Analysis of an evidence-based review and the MTA study findings.
  • Evaluation of stimulant medications, tricyclic antidepressants, and behavioral therapies.

Main Results:

  • Stimulants, including methylphenidate (MPH), are the most effective ADHD treatment.

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  • MPH and combined MPH with behavioral therapy outperformed behavioral therapy alone.
  • Stimulants were more effective than nonpharmacologic therapies, despite methodological limitations in studies.

    • Conclusions:

    • Stimulant medications are the primary effective treatment for ADHD.
    • Evidence does not support the superiority of combination multimodal treatment over stimulant therapy alone.
    • Further rigorous studies are needed to compare stimulants with other agents like tricyclic antidepressants.