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In vitro activity of four fluoroquinolones against Mycobacterium tuberculosis
J C Rodríguez1, M Ruiz, A Climent
1Section of Microbiology, Hospital General Universitario de Elche, Universidad Miguel Hernández, 03202 Elche Alicante, Spain. jcrd@retemail.es
International Journal of Antimicrobial Agents
|April 3, 2001
Abstract:
The in vitro activity of ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin against strains of Mycobacterium tuberculosis was studied. Moxifloxacin and levofloxacin showed the greatest activity having an MIC(90) of 1 mg/l. The MIC(90) for ofloxacin was 2 mg/l and for ciprofloxacin 4 mg/l. Further studies should be made to determine the role played by these compounds in the treatment of tuberculosis.