Linking proteome and genome: how to identify parasite proteins
P D Ashton1, R S Curwen, R A Wilson
1Dept. Biology, University of York, PO Box 373, YO10 5YW, York, UK. pda2@york.ac.uk
Trends in Parasitology
|April 3, 2001
Abstract:
Parasite genome projects are generating an avalanche of sequence data. If this resource is to be exploited effectively for drug and vaccine design, there is an urgent need to make the link between these DNA sequences and the functional proteins of the parasite, which they encode. Here, we seek to demystify the revolutionary advances in protein identification based on mass spectrometry.
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