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Isolation of a gene encoding a putative polyamine transporter from Candida albicans, GPT1
M D McNemar1, J A Gorman, H R Buckley
1Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Yeast (Chichester, England)
|April 3, 2001
Abstract:
A gene encoding a transport protein from the pathogenic yeast, Candida albicans, has been isolated during a complementation experiment utilizing an ornithine decarboxylase-negative (spe1 Delta) strain of Saccharomyces cerevisiae. This gene restores gamma-aminobutyric acid (GABA) transport to a GABA transport-negative mutant of S. cerevisiae and encodes a protein which putatively allows transport of one or more of the polyamines. We have assigned the name GPT1 (GABA/polyamine transporter) to this gene.