Related Experiment Video
Updated: Oct 8, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
Exposure to pets and atopy-related diseases in the first 4 years of life
P Nafstad1, P Magnus, P I Gaarder
1Department of Population Health Sciences, National Institute of Public Health, Oslo, Norway.
Insights
Early-life pet exposure may reduce the risk of atopy-related diseases in children. This study investigated the association between pet ownership and conditions like asthma and eczema in Norwegian children.
Area of Science:
- Pediatrics
- Environmental Health
- Epidemiology
Background:
- The relationship between early-life pet exposure and atopy-related diseases remains unclear.
- Atopy-related diseases, such as asthma and eczema, are common in childhood.
Purpose of the Study:
- To investigate the association between early-life pet exposure and the risk of developing atopy-related diseases in children.
- To analyze data from a Norwegian birth cohort to understand this relationship.
Main Methods:
- A population-based cohort of 2531 Norwegian children was followed from birth to age 4.
- Data on pet exposure, confounders, and atopy-related diseases were collected via questionnaires.
Main Results:
- Early-life pet exposure showed a reduced odds ratio for allergic rhinitis (0.6) and atopic eczema (0.7) at specific ages.
- Associations for bronchial obstruction and asthma were not statistically significant, but trends suggested potential risk reduction.
Conclusions:
- Early-life pet exposure may be associated with a reduced risk of developing atopy-related diseases in childhood.
- Lifestyle factors or selection bias related to pet ownership could influence these findings.
Background:
It is still unclear how early-life exposure to pets is related to children's risk of developing atopy-related diseases. We estimated associations between early-life exposure to pets and atopy-related diseases at 0-4 years of life in a cohort of Norwegian children.
Methods:
A population-based cohort of 2531 children born in Oslo, Norway, was followed from birth to the age of 4 years. Information on early-life exposure to pets, a number of possible confounders, and atopy-related diseases was mainly collected by questionnaire.
Results:
In logistic regression analysis adjusting for potential confounders, the odds ratio for being exposed to pets in early life (reference category: not exposed) was, for bronchial obstruction at 0-2 years of life, 1.2 (95% confidence interval 0.9, 1.8); for asthma at the age of 4 years, 0.7 (0.5, 1.1); for allergic rhinitis at the age of 4 years, 0.6 (0.4, 1.0); and for atopic eczema at 0-6 months of life, 0.7 (0.5, 0.9).
Conclusions:
The results indicate that early-life exposure to pets or lifestyle factors associated with exposure to pets reduce the risk of developing atopy-related diseases in early childhood. However, these findings might also be explained by selection for keeping pets.
Related Concept Videos
Asthma I: Introduction
Allergic Reactions
Asthma-I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Chronic Obstructive Pulmonary Disease I: Introduction
