[Preparation of biological bone carrier]

A series of studies on biological bone carrier (BBC), including preparation methods, components analysis, animal implantation test, biomechanical strength, ultrastructure, cross antigenicity and clinical application are reported in this article. Comprehensive process was adopted to reduce the antigen of BBC. As a substitute for bone, BBC has the following merits: (1) good biocompatibility; (2) suitable mechanical strength; (3) natural porous structure and porosity; (4) absorbability and replaceability in host; (5) unlimited sources, ready availability and simplicity in process and storage; (6) both functions of osteoconductability and osteoinductability can be developed after BBC combined with BMP.