Parental cancer as a risk factor for nine common childhood malignancies

The nationwide Swedish Family-Cancer Database was used to analyse childhood tumours among 8158 offspring by parental cancers. The results showed 2-fold familial increases for nervous system cancers and lymphomas, a 6.4-fold increase for endocrine tumours, a 60-fold increased risk for retinoblastomas but no excess risk for leukaemia and Wilms tumour.