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Modulating the immune response with dendritic cells and their growth factors
B Pulendran1, J Banchereau, E Maraskovsky
1Baylor Institute for Immunology, Dallas, TX 75204, USA. balip@baylordallas.edu
Trends in Immunology
|April 5, 2001
Abstract:
Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment, DCs and T cells in a mechanism that results in a flexible determination of T-cell polarization.