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Three down and counting: the transformation of human mammary cells from normal to malignant in three steps
1Cancer and Tissue Biology, Life Sciences Division, Building 74-174, 1 Cyclotron Road, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. MHBarcellos-Hoff@lbl.gov
Trends in Molecular Medicine
|April 5, 2001
Abstract:
An array of genetic mutations associated with human breast cancers has been identified. However, which specific combination of mutations permit normal cells to form breast cancer remains unknown. Elenbaas et al. recently described an experimental system for studying the genetic requirements for the development of breast cancer.
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