Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Membrane separations in biotechnology.

R van Reis1, A Zydney

  • 1Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA. rvr@gene.com

Current Opinion in Biotechnology
|April 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Implanted renal replacement for end-stage renal disease.

Panminerva medica·2011
Same author

Small molecule clearance in ultrafiltration/diafiltration in relation to protein interactions:Study of citrate binding to a Fab.

Biotechnology and bioengineering·2009
Same author

The impact of protein exclusion on the purity performance of ion exchange resins.

Biotechnology and bioengineering·2008
Same author

Linear scale ultrafiltration.

Biotechnology and bioengineering·2008
Same author

High performance tangential flow filtration.

Biotechnology and bioengineering·2008
Same author

An exclusion mechanism in ion exchange chromatography.

Biotechnology and bioengineering·2006
Same journal

Microbial C1 assimilation pathways for chemical synthesis: from native metabolism to synthetic design.

Current opinion in biotechnology·2026
Same journal

Medicinal plants fermentation: current knowledge and perspectives.

Current opinion in biotechnology·2026
Same journal

Fermented foods: lessons learned from metagenomics.

Current opinion in biotechnology·2026
Same journal

Microfluidic platforms for the transient transfection of mammalian cells: recent developments and challenges.

Current opinion in biotechnology·2026
Same journal

Harvesting insights from recent advances in yeast genomics for predictable and precision wine fermentation.

Current opinion in biotechnology·2026
Same journal

Minimal enzyme cascades for the aromatic-to-aromatic upgrading of lignin monomers.

Current opinion in biotechnology·2026
See all related articles

Membrane filtration is crucial in biotechnology for sterile filtration, purification, and viral clearance. Advances in membrane technology are enabling high-resolution separations and next-generation bioprocessing.

Area of Science:

  • Biotechnology
  • Bioprocessing Engineering
  • Separation Science

Background:

  • Membranes are essential in biotechnology for critical steps like sterile filtration of media and buffers.
  • Microfiltration, ultrafiltration, and depth filtration are widely employed for medium exchange, harvest, and clarification.
  • Filtration plays a key role in viral clearance strategies for mammalian cell processes.

Purpose of the Study:

  • To highlight the integral role of membranes in current biotechnology processes.
  • To discuss the advancements in membrane technology for high-resolution applications.
  • To emphasize the future impact of improved membranes on next-generation bioprocessing.

Main Methods:

  • Review of established membrane filtration techniques including microfiltration, ultrafiltration, and depth filtration.

Related Experiment Videos

  • Discussion of advanced membrane applications such as high-performance tangential flow filtration.
  • Exploration of emerging membrane technologies for enhanced separation capabilities.

    • Main Results:

    • Membrane filtration is a standard practice for sterile filtration, purification, and viral clearance in the biopharmaceutical industry.
    • Current advancements focus on high-resolution applications like improved protein-virus separation and enhanced membrane chromatography.
    • Improved membrane technologies are poised to significantly impact future biotechnology processes.

    Conclusions:

    • Membranes are indispensable tools in modern biotechnology, underpinning critical separation and purification steps.
    • Ongoing innovations in membrane science are driving progress towards more efficient and precise bioprocessing.
    • The evolution of membrane technology will be central to the development of next-generation biotechnology solutions.