Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Selective stimulation of cat sciatic nerve using an array of varying-length microelectrodes.

A Branner1, R B Stein, R A Normann

  • 1The Center for Neural Interfaces, Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112, USA.

Journal of Neurophysiology
|April 5, 2001
PubMed
Summary

A new neural interface, the Utah Slanted Electrode Array (USEA), offers improved selective muscle stimulation for spinal cord injury and stroke recovery. This device enables graded force recruitment for better motor function restoration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intraspinal microstimulation produces over-ground walking in anesthetized cats.

Journal of neural engineering·2016
Same author

Restoring motor control and sensory feedback in people with upper extremity amputations using arrays of 96 microelectrodes implanted in the median and ulnar nerves.

Journal of neural engineering·2016
Same author

Behavioral and cellular consequences of high-electrode count Utah Arrays chronically implanted in rat sciatic nerve.

Journal of neural engineering·2014
Same author

Real-time control of walking using recordings from dorsal root ganglia.

Journal of neural engineering·2013
Same author

A new high-density (25 electrodes/mm²) penetrating microelectrode array for recording and stimulating sub-millimeter neuroanatomical structures.

Journal of neural engineering·2013
Same author

Spatial and temporal characteristics of V1 microstimulation during chronic implantation of a microelectrode array in a behaving macaque.

Journal of neural engineering·2012

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Rehabilitation Technology

Background:

  • Restoring motor function after spinal cord injury or stroke is challenging due to the lack of effective peripheral nervous system interfaces.
  • Existing interfaces struggle to provide selective stimulation and graded force recruitment for numerous muscle groups.

Purpose of the Study:

  • To evaluate the stimulation capabilities of the novel Utah Slanted Electrode Array (USEA) for peripheral nerve interfacing.
  • To assess the USEA's ability to achieve selective muscle activation and graded force recruitment.

Main Methods:

  • The USEA, featuring 100 electrodes, was implanted into cat sciatic nerves for acute experiments.
  • Stimulation selectivity and recruitment properties were analyzed by recording muscle force output in response to individual and paired electrode stimulation.

Related Experiment Videos

Main Results:

  • Individual electrodes demonstrated selective stimulation of single muscle groups at low currents, with some co-activation at higher currents.
  • The USEA exhibited broader recruitment curves and lower twitch thresholds compared to cuff electrodes.
  • Specific electrode pair combinations showed overlapping or independent fiber population activation within fascicles.

Conclusions:

  • The USEA facilitates more selective muscle stimulation at lower intensities.
  • This neural interface offers improved graded recruitment of individual muscles compared to conventional cuff electrodes.
  • The USEA holds promise for rehabilitation and neuroscience applications requiring precise peripheral nerve control.