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Assessment of left ventricular function by real-time 3-dimensional echocardiography compared with conventional
1Division of Cardiology, Department of Medicine, Columbia University, New York, NY, USA.
Summary
Real-time 3-dimensional echocardiography accurately quantifies left ventricular ejection fraction, offering a valuable alternative to conventional methods. This advanced technique shows strong correlation and reduced variability compared to 2D echocardiography.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Quantitative assessment of left ventricular ejection fraction (LVEF) is crucial for cardiac evaluation.
- Multigated radionuclide angiography (MUGA) is a standard for LVEF measurement.
- Conventional 2D echocardiography has limitations in accurate LVEF quantification.
Purpose of the Study:
- To compare the accuracy of real-time 3-dimensional echocardiography (RT3DE) with MUGA for LVEF assessment.
- To evaluate the correlation between RT3DE and 2D echocardiography against MUGA.
- To assess interobserver variability between RT3DE and 2D echocardiography methods.
Main Methods:
- Real-time 3-dimensional echocardiography was performed in 56 patients undergoing MUGA.
- LVEF was calculated using RT3DE (parallel plane-disks and sector plane-disks methods) and 2D echocardiography.
- RT3DE and 2D echocardiography results were compared with MUGA in 43 patients.
Main Results:
- RT3DE demonstrated good correlation with MUGA (r = 0.87 and 0.90).
- 2D echocardiography showed significant departure from MUGA (P <.001).
- RT3DE exhibited significantly lower interobserver variability than 2D echocardiography (P <.05).
Conclusions:
- RT3DE provides accurate quantitative assessment of left ventricular ejection fraction.
- RT3DE is a reliable alternative to conventional methods for LVEF quantification.
- Adequate image quality is necessary for successful RT3DE application.