Related Experiment Videos

Solid-phase synthesis of 2,4-diaminoquinazolines

Z Wu¹, J Kim, R M Soll

¹3-Dimensional Pharmaceuticals, Inc., Eagleview Corporate Center, Exton, Pennsylvania 19341, USA.

Biotechnology and Bioengineering

|April 5, 2001

Abstract:

A highly efficient and versatile solid-phase synthesis of 2,4-diaminoquinazoline library from 2,4-dichloroquinazolines and amines using 3,5-dimethoxy 4-formylphenoxy-polystyrene resin is described.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

Synthesis and biological activity of oxo-7H-benzo[e]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists.

Bioorganic & medicinal chemistry letters·1999

Ca2+-channel-dependent and -independent inhibition of exocytosis by extracellular ATP in voltage-clamped rat adrenal chromaffin cells.

Pflugers Archiv : European journal of physiology·1998

Phenobarbital alters protein binding to the CYP2B1/2 phenobarbital-responsive unit in native chromatin.

The Journal of biological chemistry·1997

Brucella abortus arginase and ornithine cyclodeaminase genes are similar to Ti plasmid arginase and ornithine cyclodeaminase.

Biochimica et biophysica acta·1997

Mutational analysis of the hepatitis C virus RNA helicase.

Journal of virology·1997

Prediction of transition to chronic atrial fibrillation in patients with paroxysmal atrial fibrillation by signal-averaged electrocardiography: a prospective study.

Circulation·1997

See all related articles