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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Meta-analysis of hypertension as a risk factor of cerebrovascular disorders in Koreans

J K Park1, C B Kim, K S Kim

  • 1Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Korea.

Journal of Korean Medical Science
|April 6, 2001
PubMed

Insights

Hypertension significantly increases the risk of cerebrovascular disorders (CVD) in Koreans, particularly hemorrhagic CVD. Further longitudinal studies are needed to confirm these findings on hypertension and stroke risk.

Area of Science:

  • Epidemiology
  • Cardiovascular Research
  • Neurology

Background:

  • Hypertension is a major global health concern.
  • Cerebrovascular disorders (CVD) represent a significant cause of morbidity and mortality.
  • Understanding risk factors for CVD in specific populations, like Koreans, is crucial.

Purpose of the Study:

  • To integrate existing research on hypertension as a risk factor for CVD in the Korean population.
  • To quantify the association between hypertension and overall, hemorrhagic, and ischemic CVD.
  • To identify research gaps and suggest future study directions.

Main Methods:

  • Systematic literature review of Korean and English studies (1980-1997).
  • Inclusion of nine epidemiologic studies with 2,271 CVD cases.
  • Meta-analysis using common odds ratios (OR) with heterogeneity and sensitivity testing.

Main Results:

  • Hypertension is a significant risk factor for overall CVD (OR: 4.10).
  • The risk is notably higher for hemorrhagic CVD (OR: 6.56) compared to ischemic CVD (OR: 3.28).
  • The association between hypertension and hemorrhagic CVD was statistically stronger than for overall or ischemic CVD.

Conclusions:

  • Hypertension is a critical and potent risk factor for both overall and specific types of CVD in Koreans.
  • Hemorrhagic CVD shows a particularly strong association with hypertension.
  • Further prospective longitudinal studies are recommended due to limitations in the current evidence base.

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