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Related Experiment Videos

Synovial sarcoma: dynamic contrast-enhanced MR imaging features.

C S van Rijswijk1, P C Hogendoorn, A H Taminiau

  • 1Department of Radiology, Leiden University Medical Center, The Netherlands.

Skeletal Radiology
|April 6, 2001
PubMed
Summary

Early tumor enhancement within 7 seconds after arterial contrast is a consistent dynamic contrast-enhanced MRI finding in synovial sarcoma. This early enhancement is the most reliable indicator among previously described malignant imaging features.

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Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Dynamic contrast-enhanced magnetic resonance (MR) imaging features like early enhancement and washout are often associated with malignancy.
  • The consistency of these features in specific tumor types, such as synovial sarcoma, requires further investigation.

Purpose of the Study:

  • To evaluate the occurrence of specific dynamic contrast-enhanced MR imaging features in synovial sarcoma.
  • To determine which of the previously described malignant imaging features are consistently present in synovial sarcoma.

Main Methods:

  • Retrospective review of dynamic contrast-enhanced MR images from 10 patients with histologically confirmed synovial sarcoma.
  • Assessment of tumor enhancement start time, pattern, and progression, correlated with histopathology.

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Main Results:

  • All synovial sarcomas demonstrated early tumor enhancement within 7 seconds of arterial contrast (mean 4.40s).
  • Enhancement patterns varied, with plateau in one and washout in five of six rapidly enhancing lesions.
  • Peripheral enhancement was infrequent, observed in only two lesions; diffuse and heterogeneous patterns were more common.

Conclusions:

  • Early enhancement (within 7 seconds) of synovial sarcoma following arterial contrast is a consistent finding.
  • Among the evaluated features, early enhancement is the most reliable indicator of synovial sarcoma on dynamic contrast-enhanced MR imaging.