Related Experiment Video
Updated: Aug 12, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
[Procedure for keratoconus detection according to the Rabinowitz-Rasheed method--personal experience]
D Wygledowska-Promieńska1, I Zawojska
1I Katedry i Kliniki Okulistyki Slaskiej AM w Katowicach.
Purpose:
The purpose of this study was to investigate sensitivity of KISA% index to compare with Klyce-Maeda and Smolek-Klyce methods in detection of early or suspected keratoconus by using AutoTopographer TMS-3 (Tomey).
Material And Methods:
At the First Department and Clinique of Ophthalmology, Silesian Medical School in Katowice, 69 eyes underwent ophthalmological examinations in patients, who did not wear contact lenses at least for 6 weeks before examination. The procedure was performed with the TMS-3 AutoTopographer (Tomey). During the study we investigated index definitions included in Keratoconus Screening Program.
Results:
The examination showed the false negative results in 29% patients with early or suspected keratoconus. Using KISA% index we detected false negative results in 5.8% patients with early or suspected keratoconus.
Conclusion:
To sum up, we can say that the KISA% index is highly sensitive and specific for diagnosing keratoconus, more useful than Klyce-Maeda and Smolek-Klyce methods. This method can be used by users of all types of videokeratoscopes.

