Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aldicarb poisoning.

C Ragoucy-Sengler1, A Tracqui, A Chavonnet

  • 1Biochemistry-Pharmacology-Toxicology, Centre Hospitalier Universitaire, Pointe à Pitre, Guadeloupe, French West Indies , France.

Human & Experimental Toxicology
|April 9, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A deadly root and the science behind it: LC-HRMS and LC-MS/MS analysis in an aconite-induced suicide.

Forensic toxicology·2025
Same author

Semaglutide and health risk: Development and validation of a LC-HRMS method for testing semaglutide in whole blood and application to real cases.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2024
Same author

Bariatric surgery and changes in metformin distribution: About a fatal case.

Journal of pharmaceutical and biomedical analysis·2024
Same author

Diatom motility and nuclear alterations are affected by sediment elutriates of agricultural streams.

Ecotoxicology and environmental safety·2020
Same author

Comparative cardiovascular safety of strontium ranelate and bisphosphonates: a multi-database study in 5 EU countries by the EU-ADR Alliance.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020
Same author

[Testing for cannabis and synthetic cannabinoids in human specimens].

Bulletin de l'Academie nationale de medecine·2020
Same journal

Establishment of a rat model of bronchopulmonary dysplasia complicated with pulmonary hypertension and its potential applications.

Human & experimental toxicology·2026
Same journal

Pulmonary iron oxide (Fe<sub>3</sub>O<sub>4</sub>) nanoparticle-biomolecule interactions modified during aging and metabolic syndrome disease progression.

Human & experimental toxicology·2026
Same journal

Retraction: Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apoptosis pathways.

Human & experimental toxicology·2026
Same journal

Inhibition of store-operated calcium entry mitigates lipopolysaccharide-induced hepatotoxicity via modulating inflammatory and oxidative stress responses.

Human & experimental toxicology·2026
Same journal

Stevioside inhibits colorectal cancer progression by regulating macrophage polarization.

Human & experimental toxicology·2026
Same journal

Predictive factors of severe outcome in glufosinate ammonium poisoning: A retrospective study in Vietnam.

Human & experimental toxicology·2025
See all related articles

Aldicarb poisoning, often from illicit use, causes severe cholinergic symptoms and low serum cholinesterase. Oxime treatment is safe and recommended, especially when the pesticide is unknown.

Area of Science:

  • Toxicology
  • Environmental Health
  • Clinical Medicine

Background:

  • Aldicarb (Temik) is a highly toxic carbamate pesticide.
  • Illicit use as a household rodenticide poses significant poisoning risks.
  • Previous reviews lack comprehensive clinical and analytical data on aldicarb poisoning.

Purpose of the Study:

  • To review aldicarb poisoning circumstances, clinical and analytical findings.
  • To discuss the efficacy and safety of oxime treatment for aldicarb intoxication.
  • To highlight the dangers of illicit aldicarb use and recommend control measures.

Main Methods:

  • Retrospective review of 18 patients and 2 deceased individuals with suspected aldicarb poisoning.
  • Clinical assessment of cholinergic symptoms (muscarinic, nicotinic, CNS).

Related Experiment Videos

  • Laboratory analysis including serum cholinesterase activity and aldicarb identification via liquid chromatography.

    • Main Results:

    • All patients exhibited severe cholinergic symptoms, with serum cholinesterase <30% of normal.
    • Common symptoms included diarrhea, fasciculations, and central nervous system depression (GCS < 8).
    • Four patients had conduction abnormalities; two died, indicating high mortality.

    Conclusions:

    • Aldicarb intoxication is consistently severe and life-threatening.
    • Oxime treatment showed no adverse effects and is advisable for unknown pesticide poisonings.
    • Stricter measures are needed to eliminate the illegal use of aldicarb.